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. 2018 May 23;9:537. doi: 10.3389/fphar.2018.00537

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Copyright © 2018 Kang, Kwon, Ryu, Lee, Lee, Kim, Lee, Oh, Lee, Lee and Kim.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Activity-guided fractionation and identification of HOD. (A) Sepbox separation and UPLC-CAD chromatogram data. (B) 30 μg/ml of eleven fractions were treated in HepG2 cells and evaluated newly biosynthesized TG. Lipid profile analyzed by TLC using [¹⁴C]-glycerol as radiolabeled substrates. (C) Chemical structure of HOD. Significance: ^∗p < 0.05 vs. control.