eTable 1.
Laboratory Findings and Timeline
| Birth | 23 months | 25 months | 27 months | 28 months | 30 months | 32 months | 34 months | 40 months | |
|---|---|---|---|---|---|---|---|---|---|
| WBCC (×103/µL) | 358.1 | 4.3 | 5.4 | 3.67 | 2.7 | 4 | 4.2 | 9.04 | 9.74 |
| ALC (×103/µL) | 3.58 | 0.12 | 0.5 | 0.6 | 0.4 | 1.2 | 1.6 | 2.32 | 3.25 |
| ANC (×103/µL) | 10.74 | 3.65 | 4.2 | 1.96 | 1.4 | 2.1 | 2.1 | 5.47 | 5.55 |
| Immunoglobulin G (mg/dL) | 612 | 208 | 1,290 | 1,560 | 1,050 | 963 | 553 | 774 | |
| CD3+ T cells (mm3) | 39 | 24 | 163 | 500 | 1,069 | 1,650 | 2,375 | ||
| CD4+ T cells (mm3) | 37 | 18 | 130 | 354 | 750 | 1,138 | 1,627 | ||
| CD8+ T cells (mm3) | 2 | 0 | 28 | 137 | 303 | 488 | 748 | ||
| CD19+ B cells (mm3) | 23 | 132 | 156 | 225 | 335 | 441 | 586 | ||
| CD16+CD56+ NK cells (mm3) | 519 | 485 | 235 | 144 | 192 | 186 | 260 | ||
| CD19+CD27+IgM− B cells (mm3) | 6 | ||||||||
| CD4+/45RA+ T cells (mm3) | 24 | 17 | 57 | 250 | 622 | 926 | 1,413 | ||
| Mitogen assay | <5% | decreased | normal | normal | normal | ||||
| Antigen assay | absent | decreased |
Abbreviations: ALC, absolute lymphocyte count; ANC, absolute neutrophil count; IgM, immunoglobulin M; NK, natural killer; WBCC, white blood cell count.