Fig. 5.

Tumorigenesis was inhibited by GMDS knockdown in xenograft mice model of lung adenocarcinoma. a Representative tumor pictures from nude mice injected subcutaneously with lung adenocarcinoma cell line H1299 cells infected with either Scr-shRNA or GMDS-shRNA. Tumor volume was examined from the 10th day after H1299 cell injections for 5 times with a frequency of 2 times a week. Nude mice were killed at the 29th day to check tumor weight. b Tumor volume in nude mice injected subcutaneously with lung adenocarcinoma cell line H1299 cells infected with either Scr-shRNA or GMDS-shRNA. Data shown here is the mean ± SEM of tumor volume from 10 nude mice in each group (**, p < 0.01). c Tumor weight in nude mice injected subcutaneously with lung adenocarcinoma cell line H1299 cells infected with either Scr-shRNA or GMDS-shRNA. Data shown are the mean ± SEM of tumor weight from 10 nude mice in each group (**, p < 0.01)