Table 1.
Characteristics ofthe patients before and one year after renal denervation.
| Characteristics of the patients | M0 | M1 | M12 | P (M0 vs M12) |
| Number (n) | 13 | 13 | 13 | |
| Age (y) | 56.1 ± 9.9 | - | - | - |
| Women (%) | 15.4 | - | - | - |
| Diabetes (%) | 23.1 | - | - | - |
| Systolic blood pressure day (mm Hg) | 157 ± 23 | 153 ± 23 | 146 ± 20 | 0.23 |
| Diastolic blood pressure day (mm Hg) | 95 ± 12 | 89 ± 17 | 91±12 | 0.46 |
| Systolic blood pressure night (mm Hg) | 140 ± 24 | 144 ± 27 | 134 ± 15 | 0.496 |
| Diastolic blood pressure night (mm Hg) | 85 ± 12 | 81 ± 15 | 83 ± 11 | 0.731 |
| BMI (Kg/m2) | 30.9 ± 6.3 | - | - | |
| eGFR (ml/min/1.73m2) | 69.5 ± 21.6 | 74.3 ± 23 | 65.2 ± 25.3 | 0.641 |
| Number of antihypertensive drugs* | 4.8 ± 1.8 | 3.1 ± 1.6 | 3.7 ± 1.7 | 0.103 |
| Angiotensin II receptor blocker (%) | 61.5 | 61.5 | 69.2 | 0.68 |
| Angiotensin converting enzyme inhibitor (%) | 23.1 | 7.7 | 7.6 | 0.277 |
| Thiazide diuretic (%) | 61.5 | 30.7 | 53.8 | 0.691 |
| Loop diuretic (%) | 30.8 | 30.8 | 38.4 | 0.68 |
| Calcium channel blocker (%) | 92.3 | 84.6 | 84.6 | 0.539 |
| Beta-blocker (%) | 69.2 | 53.9 | 46.2 | 0.234 |
| Other antihypertensive (%) | 76.9 | 38.5 | 61.5 | 0.395 |
| Sodium excretion (mmol/24 h) | 154 ± 95 | 190 ± 117 | 144 ± 21 | 0.839 |
Values are presented as mean (SD) or percentages. –, Not applicable; M0, before renal denervation; M12, 12 months after renal denervation; P, p value; BMI, body mass index; eGFR, estimated glomerular filtration rate.
*
The daily number of antihypertensive drugs outside the study day at screening and after one year (M12).