Table 2.

Hormones before andafter renal denervation at rest and during LBNP.

Variable	Period	Before LBNP	LBNP	P
Norepinephrine (nM)	M0	1.68 (1.32; 2.13)	1.91 (1.53; 2.40)	0.039
	M1	1.63 (1.30; 2.05)	1.98 (1.66; 2.38)	0.055
	M12	1.81 (1.42; 2.32)	2.02 (1.67; 2.44)	0.279
	mixed model	P = 0.666
	M1 vs. M0	P = 0.823
	M12 vs. M0	P = 0.519
Epinephrine (nM)	M0	0.099 (0.057; 0.171)	0.167 (0.104; 0.266)	0.015
	M1	0.063 (0.033; 0.120)	0.110 (0.061; 0.197)	0.208
	M12	0.095 (0.053; 0.172)	0.110 (0.055; 0.224)	0.624
	mixed model	P = 0.342
	M1 vs. M0	P = 0.192
	M12 vs. M0	P = 0.939
PRA (ng/ml/h)	M0	0.234 (0.095; 0.575)	0.207 (0.102; 0.421)	0.84
	M1	0.279 (0.117; 0.664)	0.291 (0.124; 0.685)	0.885
	M12	0.525 (0.213; 1.30)	0.609 (0.246; 1.51)	0.181
	Mixed model	P = 0.236
	M1 vs. M0	P = 0.780
	M12 vs. M0	P = 0.111
Aldosterone (pg/ml)	M0	83.3 (53.9; 112.7)	72.3 (44.0; 118.8)	0.753
	M1	43.7 (30.6; 62.5)	42.2 (34.0; 53.0)	0.65
	M12	66.5 (37.8; 116.8)	60.6 (35.1; 104.3)	0.162
	Mixed model	P = 0.038
	Baseline vs. M1	P = 0.021
	Baseline vs. M12	P = 0.833

Results are geometric means with 95% confidence interval. PRA, plasma renin activity; M0, before renal denervation; M1, 1 month after renal denervation, M12: 12 months after renal denervation