Table 3.

Hemodynamics beforeand after renal denervation at rest and during LBNP.

Variable	Period	Before LBNP	LBNP	P
SBP (mmHg)	M0	154 ± 23	161 ± 20	0.036
	M1	158 ± 23	163 ± 23	0.008
	M12	149 ± 18	151 ± 19	0.320
	Mixed model	P = 0.116
	M1 vs. M0	P = 0.348
	M12 vs. M0	P = 0.249
DBP (mmHg)	M0	85 ± 11	92 ± 11	0.002
	M1	88 ± 13	91 ± 13	0.024
	M12	84 ± 11	86 ± 10	0.069
	Mixed model	P = 0.114
	M1 vs. M0	P = 0.157
	M12 vs. M0	P = 0.535
MBP (mmHg)	M0	108 ± 13	115±11	0.003
	M1	111 ± 14	115±13	0.002
	M12	106 ± 10	108±10	0.097
	mixed model	P = 0.136
	M1 vs. M0	P = 0.245
	M12 vs. M0	P = 0.410
HR (bpm)	M0	58 ± 11	60 ± 9	0.134
	M1	63 ± 11	63 ± 11	0.706
	M12	64 ± 12	63 ± 11	0.453
	mixed model	P = 0.030
	M1 vs. M0	P = 0.054
	M12 vs. M0	P = 0.011
GFR (mL/min)	M0	78 ± 32	67 ± 31	0.011
	M1	79 ± 34	72 ± 31	0.171
	M12	66 ± 26	63 ± 40	0.643
	Mixed model	P = 0.012
	M1 vs. M0	P = 0.903
	M12 vs. M0	P = 0.012
RPF (mL/min)	M0	353 ± 132	297 ± 94	0.039
	M1	380 ± 138	360 ± 149	0.339
	M12	429 ± 76	378 ± 148	0.225
	Mixed model	P = 0.127
	M1 vs. M0	P = 0.459
	M12 vs. M0	P = 0.044
FF (%)	M0	22.6 ± 0.054	22.3 ± 0.058	0.851
	M1	20.9 ± 0.052	21.0 ± 0.056	0.903
	M12	15.1 ± 0.053	16.1 ± 0.062	0.388
	Mixed model	P = 0.001
	M1 vs. M0	P = 0.378
	M12 vs. M0	P < 0.001
RVR (mm Hg/mL/min)	M0	0.222 ± 0.148	0.247 ± 0.086	0.028
	M1	0.195 ± 0.087	0.233 ± 0.144	0.152
	M12	0.145 ± 0.040	0.204 ± 0.14	0.075
	Mixed model	P = 0.113
	M1 vs. M0	P = 0.659
	M12 vs. M0	P = 0.045

Results are mean ± SD or median with interquartiles, SBP, systolic blood pressure; DBP, diastolic blood pressure; MBP, mean blood pressure; HR, heart rate; RPF, renal plasma flow; GFR, glomerular filtration rate; FF, filtration fraction; RVR, renal vascular resistance; M0, before renal denervation; M1, 1 month after renal denervation; M12, 12 months after renal denervation.