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. 2018 May 29;18:242. doi: 10.1186/s12879-018-3156-z

Table 2.

Impact of precise co-morbidities on the development of sepsis

Co-morbidity Odds ratio 95% confidence intervals p-value
Patients with acute pyelonephritis
 Type 2 diabetes mellitus 1.31 1.02–1.68 0.033
 Chronic heart failure 1.93 1.39–2.69 < 0.0001
 Chronic renal disease 29.31 9.26–92.86 < 0.0001
 Non-metastatic solid tumor malignancy 2.03 1.40–2.89 < 0.0001
 Corticosteroid intake 2.08 1.08–3.98 0.028
 Stroke 1.70 1.21–2.39 0.002
 Dementia 1.97 1.37–2.84 < 0.0001
Patients with community-acquired pneumonia
 Type 2 diabetes mellitus 1.73 1.06–2.82 0.027
 Chronic heart failure 1.99 1.13–3.49 0.016
 Coronary heart disease 3.72 1.69–8.19 0.001
 Dementia 3.44 1.64–7.24 0.001
Patients with intraabdominal infections
 Type 2 diabetes mellitus 3.29 2.15–5.03 < 0.0001
 Chronic renal disease 26.77 3.51–204.37 0.002
 Corticosteroid intake 3.86 1.41–10.53 0.008
 Atrial fibrillation 2.73 1.41–5.28 0.003
 Dementia 9.33 3.79–22.97 < 0.0001
 Liver cirrhosis 9.16 1.06–79.53 0.044
Patients with primary bacteremia
 Dementia 8.55 1.12–65.20 0.038

Only variables remaining significant after the final step of logistic forward conditional regression analysis are included