Table 2.
Impact of precise co-morbidities on the development of sepsis
| Co-morbidity | Odds ratio | 95% confidence intervals | p-value |
|---|---|---|---|
| Patients with acute pyelonephritis | |||
| Type 2 diabetes mellitus | 1.31 | 1.02–1.68 | 0.033 |
| Chronic heart failure | 1.93 | 1.39–2.69 | < 0.0001 |
| Chronic renal disease | 29.31 | 9.26–92.86 | < 0.0001 |
| Non-metastatic solid tumor malignancy | 2.03 | 1.40–2.89 | < 0.0001 |
| Corticosteroid intake | 2.08 | 1.08–3.98 | 0.028 |
| Stroke | 1.70 | 1.21–2.39 | 0.002 |
| Dementia | 1.97 | 1.37–2.84 | < 0.0001 |
| Patients with community-acquired pneumonia | |||
| Type 2 diabetes mellitus | 1.73 | 1.06–2.82 | 0.027 |
| Chronic heart failure | 1.99 | 1.13–3.49 | 0.016 |
| Coronary heart disease | 3.72 | 1.69–8.19 | 0.001 |
| Dementia | 3.44 | 1.64–7.24 | 0.001 |
| Patients with intraabdominal infections | |||
| Type 2 diabetes mellitus | 3.29 | 2.15–5.03 | < 0.0001 |
| Chronic renal disease | 26.77 | 3.51–204.37 | 0.002 |
| Corticosteroid intake | 3.86 | 1.41–10.53 | 0.008 |
| Atrial fibrillation | 2.73 | 1.41–5.28 | 0.003 |
| Dementia | 9.33 | 3.79–22.97 | < 0.0001 |
| Liver cirrhosis | 9.16 | 1.06–79.53 | 0.044 |
| Patients with primary bacteremia | |||
| Dementia | 8.55 | 1.12–65.20 | 0.038 |
Only variables remaining significant after the final step of logistic forward conditional regression analysis are included