Table 4.
Typical AD (n = 10) | Atypical AD (n = 9) | p-value | |
---|---|---|---|
Male, n | 2 | 7 | < .05 |
Age at death | 81 (± 10) | 63 (± 3) | < .01 |
Disease duration | 5 (± 3) | 4 (± 2) | .78 |
Brain weight (grams) | 1043 (± 146) | 1117 (± 161) | .32 |
PMI (h:min) | 6:19 (± 1:48) | 5:51 (± 1:33) | .66 |
NFT stage [7] n per stage 4/5/6 | 2/5/3 | 0/4/5 | .46 |
Amyloid stage [7] n per stage O/A/B/C | 0/0/10 | 0/1/8 | .47 |
ApoE genotype n per category 32/33/42/43/44 | 1/2/0/6/1 | 0/3/1/3/2 | .48 |
Data in mean (± SD). Age at death and disease duration in years. Mann-Whitney U test for continuous data. Fisher’s exact test for categorical data
AD Alzheimer’s disease, NFT neurofibrillary tangle, PMI post-mortem interval