Fig. 3.

The effects of APOBEC3B on cell viability at different time point (24 hr, 48 hr, and 72 hr) of ovarian cancer cell lines. a and b A2780 and HO-8910PM cells were transfected with scrambled siRNA, APOBEC3B siRNA 1 or APOBEC3B siRNA 2, cell viability and APOBEC3B expression were detected by SRB assay (the upper panels) and western blotting analysis (the lower panels), respectively. c and d SKOV3 and HEY cells were transfected with Vector or pLenti-APOBEC3B, cell viability and APOBEC3B expression were detected by SRB assay (the upper panels) and western blotting analysis (the lower panels), respectively. Data are presented as mean ± SEM (n = 3) *p < 0.05, compared with control cells. A representative blot of triplicate blots is shown. GAPDH was used as the loading control