Table 1.

Assessment of correlation between levels of siRNA-mediated LRP knockdown and viability, apoptotic levels and caspase-3 activity of early (SW-480) and late (DLD-1) stage colorectal cancer cells, using Pearson’s correlation co-efficients (R)

Cell line	SW-480	DLD-1
Correlation between total LRP levels before and after siRPSA #1 transfection (R-value)	0.91	0.96
Correlation between siRPSA #1-mediated LRP knockdown and reduction in cell viability (R-value)	0.99	0.98
Correlation between siRPSA #2-mediated LRP knockdown and reduction in cell viability (R-value)	0.99	0.93
Correlation between total levels of apoptosis and total LRP levels after siRPSA #1 transfection (R-value)	0.99	0.98
Correlation between increases in caspase-3 activity and total LRP levels after siRPSA #1 (R-value)	0.94	0.93