Table 10.
FICI calculated for five different antibiotic combinations for MDR E. cloacae isolates
| No. | SAM + CRO
|
SAM + AK
|
AK + LEV
|
SAM + MEM
|
CT + MEM
|
|||||
|---|---|---|---|---|---|---|---|---|---|---|
| FICI | Interpretation | FICI | Interpretation | FICI | Interpretation | FICI | Interpretation | FICI | Interpretation | |
| 1 | 0.75 | Additive | 0.5 | Synergism | 1.3 | Indifference | 1.16 | Indifference | 1.3 | Indifference |
| 2 | 1.16 | Indifference | 0.5 | Synergism | 1.16 | Indifference | 1.16 | Indifference | 1 | Additive |
| 3 | 1.3 | Indifference | 0.6 | Additive | 1.3 | Indifference | 1.3 | Indifference | 2 | Indifference |
| 4 | 1.16 | Indifference | 0.5 | Synergism | 1.16 | Indifference | 1.16 | Indifference | 1 | Additive |
Note: Synergism ≤0.5, additive >0.5–1, indifference >1–4.0, antagonism >4.
Abbreviations: FICI, fractional inhibitory concentration index; MDR, multidrug resistant; E. cloacae, Enterobacter cloacae; SAM, ampicillin/sulbactam; CRO, ceftriaxone; AK, amikacin; LEV, levofloxacin; MEM, meropenem; CT, colistin.