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. 2018 May 25;11:3141–3147. doi: 10.2147/OTT.S143465

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© 2018 Chen et al. This work is published and licensed by Dove Medical Press Limited

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Overexpression of miR-134 enhances Ara-C sensitivity and induces apoptosis in K562/A02 and HL-60/ADM cells.

Notes: (A) Relative expression of miR-134 in K562/A02 and HL-60/ADM cells transfected with miR-134 mimics and negative control. (B) Effect of miR-134 on cell proliferation in K562/A02 and HL-60/ADM cells transfected with miR-134 mimics and negative control. (C) Representative images of colony formation assay of K562/A02 and HL-60/ADM cells transfected with miR-134 mimics and negative control and treated with Ara-C. (D) Effect of miR-134 on cell apoptosis in K562/A02 and HL-60/ADM cells transfected with miR-134 mimics and negative control and treated with Ara-C. *p<0.05, **p<0.01.

Abbreviations: Ara-C, cytarabine; IC₅₀, half maximal inhibitory concentration; NC, normal control.