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. 2018 May 25;13:3069–3080. doi: 10.2147/IJN.S165232

Figure 5.

Figure 5

In vivo antitumor effect.

Notes: (A) Infrared thermographic images of tumor-bearing mice after treatment with PBS, gemcitabine, MWNTs, MWNTs-Ge and MWNTs-Ge-Le followed by laser irradiation. The scale bar is different for each image. (B) Average tumor volume in a Mcf-7 tumor-bearing mice model of treatment without laser in vivo. (C) Average tumor volume in a Mcf-7 tumor-bearing mice model of treatment with laser in vivo. The relative tumor volumes were normalized to their initial size (n=4 for each group). The bars are presented as mean ± SEM (unpaired t-test, *P<0.05 compared with all the other experimental groups; ▲P<0.05 compared with PBS group, gemcitabine group, MWNTs group and MWNTs-Ge group).

Abbreviations: Mcf-7, Michigan cancer foundation-7; MWNTs, multiwalled carbon nanotubes; MWNTs-Ge, multiwalled carbon nanotubes/gemcitabine; MWNTs-Ge-Le, multiwalled carbon nanotubes/gemcitabine/lentinan; NIR, near-infrared; PBS, phosphate-buffered solution; SEM, standard error of the mean.