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YM155 inhibited the upregulation of survivin induced by radiation in ESCC cells. (A) ESCC cells were harvested and the cell lysates were subjected to immunoblot analysis with antibodies against survivin. (B) Survivin was detected 72 h after 8 Gy radiation with or without YM155 treatment. β-actin was used as an internal control.
Abbreviations: ESCC, esophageal squamous cell carcinoma; IR, irradiation.
