Table 3.

The pharmacodynamics results for the combination of Apatinib and chemotherapy drugs

Groups	Apatinib	TAX	T+A	L-OHP	L+A	5-FU	F+A
T/C (%)	39.33**	66.75*	33.09**,Δ	75.64*	29.19**,Δ	83.65	26.73**,ΔΔ

Notes:

^*P<0.05 medication group vs control group,

^**P<0.01 medication group vs control group;

^ΔP<0.05 combination group vs chemotherapy group,

^ΔΔP<0.01 combination group vs chemotherapy group. T/C (%): relative tumor proliferation rate (%)/relative tumor volume for control group × 100%; T+A: TAX + apatinib; L+A: L-OHP + apatinib; F+A: 5-FU + apatinib.

Abbreviations: 5-FU, 5-fluorouracil; L-OHP, oxaliplatin; TAX, paclitaxel.