Table 1.
Baseline characteristics of patients according to the severity of carotid atherosclerosis
| Mild group | Moderate group | Severe group | F value/χ2 p | |
|---|---|---|---|---|
| (n = 87) | (n = 105) | (n = 64) | ||
| Gender (M/F) | 55/32 | 64/44 | 40/24 | 0.653 > 0.05 |
| Age (years) | 75.52 ± 3.32 | 76.21 ± 7.21 | 76.01 ± 5.21 | 0.487 > 0.05 |
| DM duration (years) | 23.89 ± 2.32 | 23.28 ± 1.26 | 24.79 ± 3.43 | 0.563 > 0.05 |
| BMI (kg/m2) | 25.13 ± 2.54 | 26.40 ± 5.24 | 28.24 ± 5.14* | 8.324 < 0.05 |
| WHR | 0.83 ± 0.13 | 0.86 ± 0.24 | 0.98 ± 0.65*△ | 11.324 < 0.01 |
| SBP (mmHg) | 135 ± 6 | 141 ± 13 | 148 ± 12* | 4.213 < 0.05 |
| DBP (mmHg) | 69 ± 4 | 67 ± 7 | 72 ± 9 | 0.672 > 0.05 |
| Medications, n (%) | ||||
| Aspirin | 26 (29.8%) | 54 (51.4%) | 48 (75%) | 6.324 < 0.05 |
| Statins | 34 (39%) | 55 (52%) | 50 (78.1%) | 7.324 < 0.01 |
| Probucol | 10 (11.4%) | 25 (23.8%) | 40 (62.5%) | 5.234 < 0.05 |
| Metformin | 35 (40.2%) | 74 (70.4%) | 55 (85.9%) | 5.341 < 0.05 |
| Acarbose | 55 (63.2%) | 76 (72.3%) | 55 (85.9%) | 0.985 > 0.05 |
| SUs | 15 (17.2%) | 27 (25.7%) | 16 (17.8%) | 0.765 > 0.05 |
| TZDs | 35 (40.2%) | 57 (54.2%) | 48 (75%) | 2.543 < 0.05 |
| Insulin | 22 (25.2%) | 46 (43.8%) | 45 (70.3%) | 4.324 < 0.05 |
Italic values indicates that, the proportions of patients that received aspirin and probucol were significantly larger in patients with severe atherosclerosis as compared with those in patients with mild atherosclerosis; while the proportions of patients were significantly different among the three groups. As for the hypoglycemic, the proportions of patients that received metformin, thiazolidones and insulin injection were significantly larger as compared with those in patients with mild atherosclerosis
DM diabetes mellitus, BMI body mass index, WHR waist hip ratio, SBP systolic blood pressure, DBP diastolic blood pressure, SUs sulfonylureas, TZDs thiazolidone
* p < 0.05 compared with the mild group; Δ p < 0.05 compared with the moderate group