Skip to main content
. Author manuscript; available in PMC: 2019 Feb 15.
Published in final edited form as: J Comp Neurol. 2017 Nov 13;526(3):425–438. doi: 10.1002/cne.24341

Figure 1. Young adult CGRPα-EGFP (GENSAT) cochlea labels medial efferents, lateral efferents and some SGNs.

Figure 1

A basal piece of a one-month-old CGRPα-EGFP (GENSAT) mouse cochlea demonstrating the labeling of medial efferents, lateral efferents and some SGNs (a few indicated with arrowheads) (a). In a more zoomed in view (b), the endings on the OHCs labeled in the CGRPα-EGFP (GENSAT) cochlea belong to medial efferents, as confirmed by co-labeling with VAChT (vesicular acetylcholine transporter) (c-d). Similarly, the co-labeling with SV2 (synaptic vesicle protein 2) confirms that the endings under the IHCs belong to the lateral efferents (e-g). Insets to the right of d and g: an enlarged view of the medial and lateral efferent endings, marked by the arrows in d and g, respectively, for better visualization of the overlapping staining. Scale bar: 100 μm in a, 10 μm in b-g, and 2 μm in the Insets.