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. 2018 May 29;18:605. doi: 10.1186/s12885-018-4502-7

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Effects of P4 on Mig-6^f/f and Mig-6^d/d mice. (A) Uterine/body ratio were significantly decreased in Mig-6^d/d mice compared to vehicle-treated Mig-6^KO mice after P4 treatment. (B) Gross morphology and (C) Hematoxylin-eosin staining after vehicle and P4 treatment. (D) Immunohistochemical analysis and quantification of Ki67 in Mig-6^f/f and Mig-6^d/d mice. The results represent the mean ± SEM. *, p < 0.05; ***, p < 0.001