Table 4.
Level of anthropometric parameters and hormones in different genotypes of rs4889 C/G in KISS1 gene in Saudi women with PCOS and Control groups
| Variable | PCOS Group (n = 28) (Mean ± SD) |
Control Group (n = 30) (Mean ± SD) |
P-value | |||||
|---|---|---|---|---|---|---|---|---|
| GG n = 11 |
CG n = 13 |
CC n = 4 |
GG n = 22 |
CG n = 7 |
GG | CG | CC | |
| Weight (Kg) | 75.8 ± 11 | 74.1 ± 13 | 58.8 ± 4.1 | 57.5 ± 10 | 68.4 ± 9.6 | 0.0001** | 0.362 | 0.157 |
| Height (cm) | 156. ± 6.8 | 156 ± 7.5 | 152 ± 5.91 | 162 ± 3.9 | 158.8 ± 3.5 | 0.007* | 0.660 | 0.468 |
| BMI (Kg/m2) | 48.3 ± 6.7 | 47.2 ± 7.5 | 38 ± 1.76 | 35 ± 8 | 42.6 ± 6.43 | 0.0001** | 0.219 | 0.157 |
| FSH (IU/I) | 6.52 ± 5.6 | 7.64 ± 5.8 | 4.9 ± 4.02 | 5.8 ± 2 | 5.5 ± 1.4 | 0.879 | 0.475 | 1.00 |
| LH (IU/I) | 13.7 ± 3.3 | 16.2 ± 3.8 | 15.3 ± 3.7 | 8.7 ± 1.2 | 8.6 ± 0.89 | 0.0001** | 0.0001** | 0.147 |
| kisspeptin (pg\mL) | 0.38 ± 0.2 | 0.43 ± 0.1 | 0.35 ± 0.18 | 0.37 ± .06 | 0.45 ± 0.06 | 0.349 | 0.968 | 1.00 |
There was only 1 sample with a CC genotype in the control group, and was not used in the comparison
*p-value< 0.05; **p-value< 0.001