Skip to main content
. 2001 Sep 25;98(21):12009–12014. doi: 10.1073/pnas.211429198

Figure 1.

Figure 1

Sequence alignment of Tdp1 orthologs. The program pileup of the GCG package was used with some manual modification to create the alignment. boxshade was used to shade residues black that are identical in ≥ 50% of the sequences and similar residues were shaded in gray. The HKD motifs are indicated by black bars above the alignment. Abbreviations and accession numbers are as follows: hs (Homo sapiens Tdp1 predicted protein FLJ11090, National Center for Biotechnology Information RefSeq accession no. NP_060789), ce (C. elegans, GenPept: AAC68960), dm (D. melanogaster glaikit protein, GenPept: CAB86488), at (A. thaliana, GenPept: CAB89327), sp (S. pombe, hypothetical protein SPCP31B10.05, PIR: T41695), sc (S. cerevisiae Tdp1, gene product of ORF YBR223c, GenPept: CAA85186). The C. elegans and A. thaliana protein sequences were predicted based on genomic sequences.