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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: Hepatology. 2018 Apr;67(4):1560–1599. doi: 10.1002/hep.29800

Table 3.

Groups at High Risk for HBV Infection Who Should Be Screened

Persons born in regions of high or intermediate HBV endemicity (HBsAg prevalence of ≥2%)
Africa All countries
North, Southeast, East Asia All countries
Australia and South Pacific All countries except Australia and New Zealand
Middle East All countries except Cyprus and Israel
Eastern Europe All countries except Hungary
Western Europe Malta, Spain, and indigenous populations of Greenland
North America Alaskan natives and indigenous populations of Northern Canada
Mexico and Central America Guatemala and Honduras
South America Ecuador, Guyana, Suriname, Venezuela, and Amazonian areas
Caribbean Antigua-Barbuda, Dominica, Grenada, Haiti, Jamaica, Saint Kitts and Nevis, Saint Lucia, and Turks and Caicos Islands
US-born persons not vaccinated as an infant whose parents were born in regions with high HBV endemicity (≥8%)*
Persons who have ever injected drugs*
Men who have sex with men*
Persons needing immunosuppressive therapy, including chemotherapy, immunosuppression related to organ transplantation, and immunosuppression for rheumatologic or gastroenterologic disorders
Individuals with elevated ALT or AST of unknown etiology*
Donors of blood, plasma, organs, tissues, or semen
Persons with end-stage renal disease, including predialysis, hemodialysis, peritoneal dialysis, and home dialysis patients*
All pregnant women
Infants born to HBsAg-positive mothers*
Persons with chronic liver disease, eg, HCV*
Persons with HIV*
Household, needle-sharing and sexual contacts of HBsAg-positive persons*
Persons who are not in a long-term, mutually monogamous relationship (eg >1 sex partner during the previous 6 months)*
Persons seeking evaluation or treatment for a sexually transmitted disease*
Health care and public safety workers at risk for occupational exposure to blood or blood-contaminated body fluids*
Residents and staff of facilities for developmentally disabled persons*
Travelers to countries with intermediate or high prevalence of HBV infection*
Persons who are the source of blood or body fluid exposures that might require post-exposure prophylaxis
Inmates of correctional facilities*
Unvaccinated persons with diabetes who are aged 19 through 59 years (discretion of clinician for unvaccinated adults with diabetes who are aged ≥60 years)*
*

Those who are seronegative should receive hepatitis B vaccine

Sources: (23, 35, 36)