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Interactions between Depdc5 and Nprl2. a & b. Large contact surfaces between Depdc5 (green) and Nprl2 (yellow) are observed from the EM density map and structural models. c & d. Surface residues on Nprl2 (c) and Depdc5 (d) participating in mediating the interactions, identified by “InterfaceResidue” script in Pymol. e-g. Loops A (e), B (f), and C (g) on Depdc5 directly contact Nprl2.
