Table 2. Worst Grade Toxicities – All Treated Patients.
Includes all events considered possibly, probably or definitely related to treatment and occurring in at least 2 patients at grade 3 or in at least 1 patient at grade 4 or higher, assessed via CTC Version 2.0.
| Patients (n=77) | |||||
|---|---|---|---|---|---|
| Grade | |||||
| 1,2 | 3 | 4 | 5 | ||
| (n) | (n) | (n) | (n) | % with grade 3–5 | |
| Hemoglobin | 64 | 7 | – | – | 9.1% |
| Lymphopenia | 39 | 16 | – | – | 20.8% |
| Neutrophils | 11 | 2 | 1 | – | 3.9% |
| Cardiac–ischemia | – | – | 2 | – | 2.6% |
| Edema | 22 | 3 | – | – | 3.9% |
| Hypotension | 5 | – | 1 | – | 1.3% |
| Thrombosis/embolism | – | 5 | 1 | – | 7.8% |
| Fatigue | 48 | 10 | 1 | – | 14.3% |
| Weight loss | 13 | 2 | – | – | 2.6% |
| Diarrhea | 18 | 4 | – | – | 5.2% |
| Nausea | 38 | 3 | – | – | 3.9% |
| Alkaline phosphatase | 23 | 4 | – | – | 5.2% |
| Bilirubin | 6 | 1 | 1 | – | 2.6% |
| SGOT | 10 | 2 | – | – | 2.6% |
| SGPT | 5 | 2 | – | – | 2.6% |
| Infection w/o neutropenia | 7 | 3 | – | – | 3.9% |
| Hyperglycemia | 4 | – | 1 | – | 1.3% |
| Cerebrovascular ischemia | – | – | 1 | – | 1.3% |
| Dizziness/lightheadedness | 6 | 1 | 1 | – | 2.6% |
| Neuropathy–sensory | 28 | 4 | 1 | – | 6.5% |
| Syncope | 1 | 2 | – | – | 2.6% |
| Arthralgia | 9 | 2 | – | – | 2.6% |
| Dyspnea | 7 | 1 | 1 | – | 2.6% |
| Pneumonitis/pulmonary infiltrates | – | 2 | – | – | 2.6% |
| Creatinine | 8 | 2 | – | – | 2.6% |
| Renal failure | – | – | – | 1 | 1.3% |
| WORST DEGREE | 29 | 38 | 9 | 1 | 62.3% |