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. Author manuscript; available in PMC: 2018 May 30.
Published in final edited form as: Neuropsychology. 2018 May;32(4):450–460. doi: 10.1037/neu0000439

Table 4.

Time-varying covariation models for MA-MCI subsample: Change in cognition as a function of change in age (γ10) and change in sensory function (γ20).

Variables Intercept γ0002 Slope γ1020 SE (slope) p-value (slope)

Digit Symbol

 Olfaction 41.73 -0.75 0.113 < .001
0.19 0.384 0.378 n.s.

 Distance vision 38.62 -0.728 0.112 < .001
4.80 -2.109 3.397 n.s.

 Audition 38.15 -0.753 0.127 < .001
0.14* 0.019 0.071 n.s.

Word Recall

 Olfaction 14.60 -0.272 0.057 < .001
-0.02 0.356 0.189 < .05#

 Distance vision 20.59 -0.273 0.056 < .001
-6.69# 2.539 1.386 < .05#

 Audition 14.38 -0.261 0.064 < .001
-0.01 -0.040 0.037 n.s.

Vocabulary

 Olfaction 42.23 -0.178 0.086 < .05
-0.09 -0.052 0.290 n.s.

 Distance vision 39.49 -0.201 0.089 < .05
0.08 -0.866 2.666 n.s.

 Audition 41.20 -0.043 0.099 n.s.
-0.06 -0.133 0.055 < .05

γ00 = Average cognitive function centered at baseline testing holding age and sensory function constant; γ02 = a person-mean centered predictor for sensory function reflecting the pure between-person effect of individual differences in olfaction, vision, and audition; γ10 = age slope (average rate of linear change per additional year of age, independent of change in sensory function); γ20 = change in sensory function slope (person-mean centered to represent pure within-person variation about one’s own mean sensory function, independent of the linear trend for age); SE = standard error. All variance components for intercept were significantly different from 0. The level-2 age predictor (γ01), centered at the grand mean (75.68 years; SD=7.23), was entered as a covariate for all models to adjust for between-person age heterogeneity upon entry into the study.

#

p < .05, one-tailed

*

p < .05

**

p<.01

***

p<.001