Figure 3. The data available through MR-Base and the possible exposure-outcome analyses that can be performed.

Exposure traits can very broadly defined and may include molecular traits like gene expression, DNA-methylation, metabolites and proteins, as well as more complex traits, including cholesterol, body mass index, smoking and education. Further details on the traits with complete summary data can be found in Supplementary file 1A. The numbers reflect MR-Base in December 2017 and are updated on a regular basis.