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. Author manuscript; available in PMC: 2018 Jun 20.
Published in final edited form as: Mucosal Immunol. 2017 Dec 20;11(3):615–626. doi: 10.1038/mi.2017.99

Figure 4. Transfers of Wt and Pla2g5-null BM-macrophages regulate Alternaria-induced pulmonary inflammation.

Figure 4

A) Pla2g5-null and Wt recipient mice received Wt (medium grey bars) or Pla2g5-null (dark gray bars) BM-macrophages intratracheally at day 2, followed by Alternaria i.n. at day 3, 6 and 9 or only Alternaria (light grey bars). Mice were euthanized 18 h after the last dose. Analysis by flow cytometry of eosinophils gated as CD45+ CD11c− SiglecF+ lung cells and expression of CD25, Sca-1 and intracellular IL-5 on Thy1.2+ ILC2s. B) Production of FFAs measured by mass spectrometry in Wt and Pla2g5-null BM-Macrophages. (A) Values are mean ± SEM of 2 independent experiments with 10–12 mice per group. (B) Data are from 3 independent experiments. # P<0.0001, *** P<0.0005, **P< 0.005, *P< 0.05.