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. Author manuscript; available in PMC: 2018 Aug 7.
Published in final edited form as: Mucosal Immunol. 2018 Feb 7;11(3):752–762. doi: 10.1038/mi.2017.118

Figure 1. Decreased production of RegIIIγ and β-defensins in IEC of GPR43−/−mice.

Figure 1

IEC from small intestine were isolated from WT and GPR43−/−mice respectively. (A) IEC expression of RegIIIγ and β-defensins 1, 3, 4 in GPR43−/−and WT mice determined by qRT-PCR and normalized against gapdh. Pooled data from 2 independent experiments. n=5 mice/group. (B) Protein levels of RegIIIγ and β-defensins were determined by Western blot. Data are reflective of 2 independent experiments. n=4 mice/group. (C) Protein/β-actin relative expression of RegIIIγ and β-defensins were compared between GPR43−/−and WT mice. Data were combined from 2 independent experiments. *p<0.05; **p<0.01.