Table 3.
Enrollment predictors of incident hypertension among all participants
| Unadjusted hazard ratio (CI, p-value) |
Adjusted hazard ratiof (CI, p-value) |
|
|---|---|---|
| Delayed group | 0.91 (0.66 – 1.26, 0.575) | – |
| Agea | 1.72 (1.45 – 2.03, <0.001) | 1.32 (1.10 – 1.59, 0.002) |
| Female | 0.94 (0.68 – 1.30, 0.707) | – |
| HIV clinical stage | ||
| Stage 1 | 1 (reference) | – |
| Stage 2 | 1.18 (0.85 – 1.64, 0.314) | – |
| Stage 3 | 0.75 (0.46 – 1.22, 0.243) | – |
| Body Mass Index (BMI)b | 1.12 (1.07 – 1.16, <0.001) | 1.07 (1.03 – 1.12, < 0.001) |
| Systolic pressure (SBP)c | 2.09 (1.88 – 2.33, <0.001) | 2.02 (1.79 – 2.27, < 0.001) |
| Diastolic pressure (SBP)c | 2.74 (2.28 – 3.30, <0.001) | – |
| eGFR <60ml/min/1.73m2 | 1.68 (0.88 – 3.20, 0.114) | – |
| CD4 T cell countd | 1.04 (0.84 – 1.30, 0.721) | – |
| Log2HIV-1 RNA levele | 1.02 (0.96 – 1.09, 0.556) | – |
| Log2C-reactive proteine | 1.05 (0.97– 1.12, 0.225) | – |
| Log2Interleukin-6e | 1.09 (0.98 – 1.21, 0.123) | 1.24 (1.12 – 1.38, < 0.001) |
| Log2D-dimere | 1.15 (0.99 – 1.34, 0.069) | – |
a
Hazard ratio, HR reported per 10-year increment.
b
HR reported per 1 kg/m2 increase in BMI.
c
HR reported per 10 mm of mercury increment.
d
HR reported per 50 cell/mm3 increment.
e
HR reported per log2 increase.
f
Adjusted for all the variables in the adjusted model (age, BMI, SBP and Log2Interleukin-6).