Table 3.
Intra-class and Spearman correlation coefficients for within-person stability over 1-year period by protein class.
| Proteins, N | ICC | Spearman r | ICC or Spearman r ≥ 0.4, % | ICC or Spearman r ≥ 0.6, % | |||
|---|---|---|---|---|---|---|---|
| Median (10th, 90th percentile) |
ICC ≥ 0.4, % | Median (10th, 90th percentile) |
r ≥ 0.4, % | ||||
| Overall | 1,305 | 0.70 (0.33, 0.94) |
87 | 0.68 (0.36, 0.87) |
87 | 91 | 72 |
| Protein Class | |||||||
| Cytokine | 138 | 0.76 (0.51, 0.93) |
95 | 0.70 (0.45, 0.87) |
94 | 97 | 80 |
| Growth factor | 79 | 0.78 (0.40, 0.94) |
90 | 0.72 (0.40, 0.85) |
90 | 92 | 82 |
| Hormone | 35 | 0.75 (0.46, 0.93) |
91 | 0.71 (0.44, 0.91) |
94 | 97 | 80 |
| Kinase | 148 | 0.68 (0.34, 0.94) |
86 | 0.64 (0.32, 0.84) |
86 | 91 | 65 |
| Protease | 168 | 0.70 (0.33, 0.92) |
85 | 0.70 (0.39, 0.85) |
89 | 92 | 75 |
| Protease inhibitor | 45 | 0.72 (0.27, 0.89) |
87 | 0.74 (0.42, 0.87) |
89 | 89 | 78 |
| Receptor | 258 | 0.77 (0.41, 0.96) |
91 | 0.72 (0.44, 0.89) |
93 | 95 | 82 |
| Structural protein | 60 | 0.68 (0.42, 0.92) |
92 | 0.67 (0.40, 0.87) |
90 | 93 | 70 |
| Other/unclassified | 499 | 0.64 (0.23, 0.93) |
82 | 0.65 (0.26, 0.86) |
82 | 86 | 66 |