Fig. 2. Topical application of VTI-1002 gel accelerates re-epithelialization and wound maturation in diabetic burn wounds.

a Representative morphology of different wound classes (IHC keratin staining). b Prevalence of wound class in vehicle control group (n = 10) and VTI-1002 treatment group (n = 17). P = 0.0063 by χ² test. Representative images of c CD45, d CD68, e vimentin, f α-SMA staining, and quantification of c CD45, d CD68, e Vimentin, f α-SMA staining intensity in the wounds at day 30 from vehicle control group and VTI-1002 treatment group (n ≥ 5 per group). Results are expressed as median and min/max value, NS = not significant, **P < 0.01, ***P < 0.001 by Student's t test. Scale bar = 100 µm