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. 2018 May 30;8:8421. doi: 10.1038/s41598-018-26525-y

Table 1.

Summary of Characteristics of Clinical Samples.

Clinical Category Non-Osteoporosis Control (NOPC) Osteopaenia* Osteoporosis*
Osteopaenia without fracture Osteopaenia with fracture** Osteoporosis without fracture Osteoporosis with fracture**
Total number of participants recruited (Female/Male) 30 (20/10) 63 (53/10) 15 (13/2) 34 (28/6) 19 (17/2)
Total nmber of >40 years old participants (Female /Male) included in the analysis 12 (11/1) 61 (52/9) 15 (13/2) 33 (27/6) 18 (16/2)
Mean age years (Mean ± SD) 67 ± 9.6 65.6 ± 9.5 67 ± 9.5 68.6 ± 10 70 ± 10
BMD (g/cm2) Mean ± SD 0.96 ± 0.07 0.83 ± 0.10 0.88 ± 0.12 0.7 ± 0.07 0.7 ± 0.1
T-Score Lumbar Spine (L2-L4) Mean ± SD 0.6 ± 1.4 −1.2 ± 0.9 −1.1 ± 1.1 −2.7 ± 0.95 −2.78 ± 1

*Four osteopaenia patients and 1 osteoporosis patient were reported as suffering from coeliac disease, 3 osteopaenia and 1 osteoporosis patients were reported to suffer from asthma and were on regular steroid medication. One osteopaenia patient was suffering from lung cancer, 1 osteopaenia patient and 4 osteoporosis patients had type-2 diabetes and 1 osteopaenia patient was suffering from type-3c (pancreatogenic) diabetes. 5 osteopaenia and 3 osteoporosis patients suffered from hypertension.

**Fractures occurred between 1 month and 2 years before the collection of blood samples.