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. 2018 May 24;9:1010. doi: 10.3389/fimmu.2018.01010

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Copyright © 2018 Khan, Alanazi, Ahmed, Vater, Assiri and Broering.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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C5a inhibition promotes gene expression and anti-inflammatory cytokine. (A–F) Quantitative RT-PCR analysis shows fold change in regulatory and proangiogenic genes IL-5, TGF-β, IL-10, IL-6, vascular endothelial growth factor (VEGF), and AGPT1 mRNA at d10 posttransplantation. (G–L) Quantitative analysis of serum cytokines (pg/ml) at d10 posttransplantation. Data are presented as means with SE of 3–4 transplants/time point/experiment, and repeats of three different experiments.