Figure 5.

Cytokine gene modulation upon Sindbis virus (SINV) + Shigella co-infection. (A–D) Cytokine (ifnphi1, il1b, tnfa, il10) induction was measured from individual zebrafish larvae sequentially co-injected with SINV + Shigella (blue) or from individual zebrafish larvae injected with SINV alone (green) or with Shigella alone (red), and non-injected fish as control (CTRL, black curves). Data plotted are from three independent experiments pooled (n = 15 larvae for each condition); individual values are shown and curves correspond to the means. Statistical analysis is shown as a table under each graph.