Table 1.

Considerations for maximum efficacy and safety of administration of keto/amino acid–supplemented protein-restricted diets

- Patient selection: motivation and ability to follow a protein-restricted diet

- Gradual implementation of intervention (i.e., progressive 0.2-g/kg body weight/day decrements over 2–4 weeks)

- Support and educational tools along with regular dietary counseling (every 2–3 months initially)

- Involvement of a multidisciplinary team, including an experienced dietician

- Close clinical follow-up