Table 4.
Subgroup univariate and multivariate association between baseline LTL and progression of albuminuria
| Progression | Univariate OR (95% CI) | P value | Multivariate OR (95% CI) | P |
|---|---|---|---|---|
| Normo- to microalbuminuria | ||||
| LTL (1-SD decrement) | 1.13 (0.91–1.40) | 0.263 | 1.17 (0.93–1.47) | 0.185 |
| Normo- or micro- to macroalbuminuria | ||||
| LTL (1-SD decrement) | 1.39 (1.03–1.87) | 0.032 | 1.54 (1.02–2.32) | 0.042 |
Data are ORs (95% CIs) estimated as per effect of 1-SD decrement in natural log LTL in univariate or multivariate model adjusted for age, gender, ethnicity, HbA1c, diabetes duration, body mass index, triglycerides, systolic blood pressure, urine albumin creatinine ratio, estimated glomerular filtration rate, and usage of renin-angiotensin system antagonist and statins. Bold values represents significant data.
CI, confidence interval; LTL, leukocyte telomere length; OR, odds ratio.