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. 2017 Dec 1;3(3):555–572. doi: 10.1016/j.ekir.2017.11.019

Figure 5.

Figure 5

Identification of extracellular vesicle (EV)–enriched microRNAs (miRNAs) from patients with type 1 diabetes (T1D). (a) Novel sequence motif identified from the 31 urine-specific EV-enriched miRNAs (see Supplementary Table S3) with an E-value of 1.1e-002 in 23 of 31 samples. Each individual miRNA site alignment with the given P value is displayed. (b) Venn diagram showing overlap (25) between 77 miRNAs from patients with T1D who showed differential concentration changes in EVs (red) with 60 EV-enriched miRNAs (blue). (c) Venn diagram showing overlap (19) of top 25 urine EV-enriched miRNAs reported from Cheng et al. 2014180 (yellow) with urine-specific EV-enriched miRNAs identified in this work (blue).