Table 2.
Selected miRNAs showing differential concentration changes between non-MA and MA persistent patients
| Starting fraction | miRNA | PMA:NO-AVE (log2CPM) | PMA:MA-AVE (log2CPM) | Log2FC | P |
|---|---|---|---|---|---|
| Urine | hsa-miR-133a-1-3p | 5.97 | 8.40 | 2.43 | 0.0254 |
| hsa-miR-31-5p | 7.95 | 9.81 | 1.85 | 0.0498 | |
| hsa-miR-122-5p | 8.96 | 10.48 | 1.52 | 0.0097 | |
| hsa-miR-99b-5p | 10.57 | 11.99 | 1.43 | 0.0324 | |
| hsa-miR-92b-3p | 8.29 | 9.49 | 1.21 | 0.0282 | |
| hsa-miR-181b-1-5p | 9.44 | 10.49 | 1.05 | 0.0077 | |
| EV | hsa-miR-182-5p | 9.80 | 11.32 | 1.52 | 0.0446 |
| hsa-miR-200c-3p | 11.83 | 13.58 | 1.76 | 0.0483 | |
| hsa-miR-30d-5p | 13.48 | 14.59 | 1.11 | 0.0414 | |
| hsa-miR-31-5p | 8.74 | 10.92 | 2.17 | 0.0457 | |
| hsa-miR-335-5p | 10.40 | 11.21 | 0.81 | 0.0142 | |
| hsa-miR-96-5p | 7.75 | 8.90 | 1.15 | 0.0298 |
AVE, average; CPM, counts per million; EV, extracellular vesicle; FC, fold change; MA, microalbuminuria; miRNA, microRNA; PMA:NO, Persistent MA: non-MA cycle; PMA:MA, Persistent MA:MA cycle.
See Supplementary Table S3 for additional details.