Table 2.

Association of medication adherence status with chronic kidney disease (CKD) progression and all-cause death (n = 3305)

Outcome	Predictor	Model 1	Model 2
CKD progression	High adherence (reference)	1.00	1.00
	Medium adherence	1.00 (0.83, 1.20)	1.08 (0.89, 1.31)
	Low adherence	1.43 (1.20, 1.70)	1.27 (1.05, 1.54)
Death	High adherence (reference)	1.00	1.00
	Medium adherence	1.05 (0.83, 1.32)	0.98 (0.76,1.28)
	Low adherence	1.34 (1.07,1.68)	1.14 (0.88, 1.47)

Data are adjusted hazard ratios with 95% confidence intervals in parentheses.

Model 1: clinical center and sociodemographic factors (age, gender, race/ethnicity, education, health insurance, and marital status).

Model 2: Model 1 plus clinical factors (diabetes, hypertension, cardiovascular disease, body mass index, estimated glomerular filtration rate, proteinuria), cardiovascular medications (angiotensin-converting enzyme inhibitor/angiotensin receptor blocker, β-blocker, statin), number of types of medications per day, and Beck Depression Inventory–II score.