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. 2018 May 24;9:611. doi: 10.3389/fphys.2018.00611

FIGURE 1.

FIGURE 1

(A) Presence of muscarinic acetylcholine M1 receptor in human neuroblastoma SK-NBE, oligodendrocytes MO3-13 and neuroblastoma-spinal motor neuron fusion cells NSC-34 M1 receptor protein bands normalized to α-tubulin. Effect of SOD1 on ERK1-2 (B) and AKT (C) activation in NSC-34 cells incubated with 400 ng/ml of SOD1 for 10 and 30 min. The data represent the means ± SEM of three independent experiments relative to control obtained by densitometric analysis of P-ERK1-2 and P-AKT protein bands normalized to ERK1-2 and AKT, respectively. p < 0.05 vs. Ctr; ∗∗p < 0.001 vs. Ctr; #p < 0.001 vs. SOD1 10 min.