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Immunohistochemistry showing c-Fos and pErk1/2 expression in WT SCN on day 1 after LD phase-advance. (A) Sampling time course. White and black bars indicate light and dark phases, respectively. (B, C) Representative images of immunoreactivity to c-Fos and pErk1/2 in WT SCN before or after jet lag. Boundaries of the SCN and the ventrolateral and the central parts are shown in the dotted lines in panel (B). oc, optic chiasma; v, third ventricle. Bar = 100 μm.
