Table 2. Prescription pattern of OACs in patients with atrial fibrillation by specialty of clinicians and type of institutes from HIRA-NPS between 2014 and 2016.
| Characteristics | Warfarin (%) | Apixaban (%) | Dabigatran (%) | Edoxaban (%) | Rivaroxaban (%) | Total (%) | P value | |
|---|---|---|---|---|---|---|---|---|
| Year | < 0.001 | |||||||
| 2014 | 15,234 (96.3) | 48 (0.3) | 361 (2.3) | 0 (0.0) | 173 (1.1) | 15,816 (100.0) | ||
| 2015 | 14,267 (76.4) | 1,011 (5.4) | 1,630 (8.7) | 0 (0.0) | 1,758 (9.4) | 18,666 (100.0) | ||
| 2016 | 10,011 (44.3) | 2,828 (12.5) | 3,436 (15.2) | 873 (3.9) | 5,455 (24.1) | 22,603 (100.0) | ||
| Specialty of clinicians | < 0.001 | |||||||
| Internal medicine | 30,247 (70.2) | 2,836 (6.6) | 3,627 (8.4) | 750 (1.7) | 5,652 (13.1) | 43,112 (100.0) | ||
| Neurology | 6,443 (61.4) | 968 (9.2) | 1,619 (15.4) | 95 (0.9) | 1,372 (13.1) | 10,497 (100.0) | ||
| Thoracic surgery | 1,441 (97.2) | 9 (0.6) | 1 (0.1) | 8 (0.5) | 23 (1.6) | 1,482 (100.0) | ||
| Others | 1,381 (69.3) | 74 (3.7) | 180 (9.0) | 20 (1.0) | 339 (17.0) | 1,994 (100.0) | ||
| Type of institutes | < 0.001 | |||||||
| Tertiary hospital | 15,937 (69.8) | 2,373 (10.4) | 1,916 (8.4) | 318 (1.4) | 2,304 (10.1) | 22,848 (100.0) | ||
| Secondary hospital | 17,942 (66.9) | 1,289 (4.8) | 2,854 (10.6) | 480 (1.8) | 4,263 (15.9) | 26,828 (100.0) | ||
| Primary clinics | 5,633 (76.0) | 225 (3.0) | 657 (8.9) | 75 (1.0) | 819 (11.1) | 7,409 (100.0) | ||
| Total prescription | 39,512 (69.2) | 3,887 (6.8) | 5,427 (9.5) | 873 (1.5) | 7,386 (12.9) | 57,085 (100.0) | ||
OACs = oral anticoagulants, HIRA-NPS = Health Insurance Review and Assessment Service-National Patient Samples.