Table 3.
Characteristics of recipients from donors older than 60 years according to period and transplant category and main transplant characteristics and outcomes. Data are numbers, mean ± SD, or median (ranges).
| Period | Pre-DKTa | DKT eraa | ||
|---|---|---|---|---|
| Tx category | SKTpre | SKTlr | SKThr | DKT |
| n | 170 | 33 | 51 | 48 |
| M/F | 115/55 | 26/7 | 36/15 | 34/14 |
| Age, years | 59 ± 7.4 | 58.5 ± 8.7 | 63.5 ± 5.7∗ | 66.7 ± 4.5∗ |
| Months on dialysis | 45 (6–298) | 50 (11–216) | 37 (5–107) | 29 (4–226) |
| 1st-2nd-3rd Tx, n | 152-15-3 | 29-4-0 | 50-0-1+ | 48-0-0+ |
| HLA-MMb | 4 (0–6) | 4 (1–6) | 4 (1–6) | 5 (3–6)∗∗ |
| Follow-upc, months/pt | 72.0 (62.6–72.0)∗∗ | 44.1 (34.0–62.0) | 43.3 (24.2–59.4) | 44.2 (26.0–64.3) |
| Total follow-up, pt-yrs | 827.4 | 126.7 | 169.6 | 176.0 |
| CIT, hrs:mind | 13:58 ± 4:08 | 14:04 ± 4:56 | 16:27 ± 3:53∗ | 16:05 ± 3:26∗ |
| PNF, n. (surg)e | 8 (4) | 1 | 6 (2) | 2 (2) |
| PNF, % | 4.7 | 3.0 | 11.7 | 4.2 |
| DGF, n (%)f | 72 (42.3) | 20 (60.6) | 25 (49,0) | 23 (47.9) |
| BPR-18mo, n (%)g | 13 (7.6) | 4 (12.1) | 10 (20.8)+ | 4 (8.3) |
| Graft failure, n (n/100 pt-yr)h | 21 (2.5) | 3 (2.4) | 10 (5.9)+ | 4 (2.3) |
| Death, n (n/100 pt-yr) | 24 (2.9) | 2 (1.6) | 7 (4.1) | 5 (2.8) |
aPre-DKT, DKT era: see Table 2. bMismatches on HLA loci A, B and DRB1; ctime to event or censoring; dcold ischemia time; egraft primary nonfunction (number of surgical failures in parenthesis); fDelayed graft function (need for dialysis in the first week post-Tx); gbiopsy-proven rejection within 18 months after transplant; hPNF and graft losses over time. Statistical differences: ∗P < 0.01 versus SKTpre and SKTlr; +P < 0.05 versus SKTpre; ∗∗P < 0.05 or less versus all other categories.