Table 1.

miRNAs participate in the regulation of liver CSCs.

miRNA	Expression	Liver CSC subtype	Targets	Reference
miR-181	↑	EpCAM+	CDX2, GATA6, NLK	[17]
miR-1246	↑	CD133+	AXIN2, GSK3β	[18]
Let7b	↓	CD24+CD133+	FZD4	[25]
miR-148a	↓	EpCAM+AFP+	ACVR1	[27]
miR-200a	↓	Side population	β-Catenin	[28]
miR-214	↓	EpCAM+	β-Catenin, EZH2	[29]
Let-7a	↓	Sphere formation	TCF4	[31]
miR-25	↑	CD133+	PTEN/PI3K/AKT/Bad	[32]
miRNA-21	↑	Side population	PTEN, RECK, PDCD4	[33]
miR-612	↓	EpCAM+CD133+	SP1/Nanog	[34]
miR-429	↑	EpCAM+	PBBP4/E2F1/OCT4	[35]
miR-145	↓	CD133+	Oct4	[36]
miRNA-200b	↓	CD13+CD24+	BMI1, CD13, CD24	[16]
miR-142-3p	↓	CD133+	CD133	[37]
miR-424, miR-222, miR-200b, let-7c	↓	α2δ1+	PBX3	[38]
miR-122	↓	CD133+	PDK4	[39]
miR-130b	↑	CD133+	TP53INP1	[40]
miR-155	↑	CD90+CD133+	TP53INP1	[41]
miR-152	↓	CD133+	KIT	[42]
miR-589-5p	↓	CD90+	MAP3K8	[43]
miR-150	↓	CD133+	c-Myb	[44]
miR-148b	↓	Side population	NRP1	[45]
miR-137	↓	CD133/44+EpCAM+	ANT2	[46]