Table 2.
Expression of MPPED2 protein levels in thyroid neoplasias analysed by immunohistochemistry.
| Histotype (n) | Reduced Expression 1 (n, %) | Whole Cohort |
|---|---|---|
| FTA 2 (n = 19) | n = 7 (37%) | p < 0.001 |
| PTC 3 (n = 147) | n = 116 (79%) | p < 0.001 |
| FTC 4 (n = 30) | n = 23 (77%) | p < 0.001 |
| PDC 5 (n = 37) | n = 32 (86%) | p < 0.001 |
| ATC 6 (n = 15) | n = 8 (53%) | p = 0.003 |
| Whole cohort p < 0.001 | ||
1 MPPED2 protein expression in thyroid carcinoma vs. the adjacent corresponding normal thyroid tissue; 2 FTA, follicular thyroid adenoma; 3 PTC, papillary thyroid carcinoma; 4 FTC, follicular thyroid carcinoma; 5 PDC, poorly differentiated carcinoma; 6 ATC, anaplastic thyroid carcinoma.