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. 2017 Dec 16;5:76–84. doi: 10.1016/j.toxrep.2017.12.013

Fig. 5.

Fig. 5

Demonstrates the importance of IGF1R in normal cellular metabolism, while BPA induced secretory pathway calcium ATPase (SPCA1) inhibition can cause reduced surface expression of IGF1R while it causes accumulation of the inactive trans-Golgi pro-IGF1R form. (Single-column fitting image).