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. 2018 Jan 12;5:196–206. doi: 10.1016/j.toxrep.2017.12.015

Table 4.

Historical Negative and Positive Control Values for Non-S9 Activated Micronucleus Assay, 2013–2015.

Micronucleated Binucleated Cells (%)
Negative Controt
Positive Controla
4 h 24 h 4 h 24 h
Mean 0.36 0.39 3.77 1.76
Standard Deviation 0.23 0.31 1.66 0.86
95% Control Limits 0.00–0.82 0.00–1.01 0.46–7.08 0.04–3.48
Rangeb 0.05–1.43 0.10–2.00 1.00–10.10 0.50–5.70
a

Positive control for non-activated 4 h studies is Mitomycin C, Positive control for activated 24 hour study is Vinblastine.

b

Range is from minimum to maximum.