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. 2018 Apr 24;9(5):226. doi: 10.3390/genes9050226

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Overall survival in MM patients with respect to SLC16A1 rs7556664 A. This SNP is in near-perfect LD with two other SLC16A1 SNPs described in this study. Allele rs7556664 A (orange curve) also corresponds to rs1049434 A and rs7169 T; however, for the sake of simplicity, only rs7556664 A is shown in the figure above. The left panel shows OS calculated for the entire group of patients, while that to the right shows overall survival (OS) calculated for thalidomide-treated patients only. The numbers at risk show numbers of patients in the risk set (i.e., patients still living, a number used to calculate survival) at a given time point on the x-axis. Survival was calculated using the Kaplan-Meier method and the real statistics resource pack for Microsoft excel.