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. 2018 May 3;9(5):240. doi: 10.3390/genes9050240

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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(A) Quantile-quantile (QQ)-plot of p-values for common variation observed in patients against 1000G-IBS controls. The green shadow indicates the p-values obtained under a permutation approach (1000 permutations). (B) Manhattan plot of common variants observed in patients against 1000G-IBS controls. The dotted line indicates the Bonferroni threshold.