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. 2018 May 9;10(5):248. doi: 10.3390/v10050248

Table 4.

Clinical features used to distinguish patients with Chikungunya fever from patients with AUFI a.

Parameter PPV (%) NPV (%) Sens (%) Spec (%) Likelihood Ratio (+) Likelihood Ratio (−)
Wrist arthralgia 96.1 44.4 90 66.6 2.72 0.13
Wrist, MCP and knee arthralgia 98 55 92.7 83.3 5.56 0.08
Wrist, MCP and knee arthralgia, plus arthritis (or adenopathy) 98 44.4 91 80 4.55 0.11
MCP and knee arthralgia plus ≥8 VAS score 96 62.5 94.2 71.4 3.29 0.08
Wrist, MCP and knee arthralgia, ≥30 joints involved, arthritis and adenopathy 96.1 66.6 94.3 75 3.77 0.07

a AUFI, acute undifferentiated febrile illness; PPV, positive predictive value; NPV, negative predictive value; Sens, sensitivity; Spec, specificity; MCP, metacarpophalangeal; VAS, visual analog scale.