Figure 2.

Morphological observations of cells after interactions with graphene-based nanomaterials. (a) Transmission Electron Microscopy (TEM) images of Mouse Embryo Fibroblasts (MEFs) treated with GO-high (GO-h), GO-medium (GO-m) and GO-low (GO-l) at 50 µg/mL for 24 h. On bottom, high-magnification images of the boxed-in photos on top are represented. The white and black arrows indicate GO aggregates inside and outside cells, respectively. (b) Scanning Electron Microscopy (SEM) images of cell membrane damage incurred by A549 cells as a result of GO nanosheets exposure observed during different phases of incubation. On bottom, high-magnification images of the boxed-in photos on top are represented. Reproduced with permissions from [40,42].